The Effects of Dentifrice Containing Sodium Bicarbonate and Triclosan on Oral Malodor
김지혜, 장연수, 신승철, 김병준, 안재현,
소속 상세정보
김지혜 ( Kim Ji-Hye ) - Dankook University Graduate School of Public Health & Social Welfare Department of Oral Health
장연수 ( Jang Yeon-Soo ) - Dankook University Graduate School of Public Health & Social Welfare Department of Oral Health
신승철 ( Shin Seung-Chul ) - Dankook University School of Dentistry Department of Preventive Dentistry
김병준 ( Kim Byung-Jun ) - LG Household & Health Care Research Park
안재현 ( Ahn Jae-Hyun ) - LG Household & Health Care Research Park
KMID : 1157520110070010041
Abstract
Objective: The object of this study is to evaluate the effect of dentifrice containing sodium bicarbonate and triclosan on the removal of kimchi and garlic odor and its 12 hours lasting efficacy.
Methods: To confirm the efficacy of dentifrice on oral malodor in-vitro and clinical trials were conducted. Antibacterial activity on P. intermedia and removal efficacy of kimchi and garlic odor were measured by GC and a Halimeter, in-vitro. Clinical trials were designed by a double blind, crossover study design for subjects aged between 20-40. The removal effect of kimchi odor and its 12 hour long-lasting inhibitory effect of oral malodor were conducted by organoleptic evaluations and/or through a Halimeter.
Results: Antibacterial activity on P. intermedia, experiment group 2 (sodium bicarbonate/triclosan), was under 100 CFU/ml. Experiment group 2 showed effective reduction in oral malodor using cultivated saliva with garlic. The result of measuring the effects removing acetic acid among the kimchi odor ingredients using GC showed that compared to the control group, the peak area of experiment group 2 decreased 52.28%. The result of sensory evaluation after brushing under the kimchi intake showed the statistically meaningful effect of oral malodor control for 2 hours after brushing than the control group (p＜0.05). In clinical tests through sensory evaluation and Halimeter measuring oral malodor the controlling effect in 12 hours after brushing, the experiment group inhibited oral malodor control more than the control group (p＜0.05).
Conclusion: It is proven that dentifrice containing sodium bicarbonate and triclosan is more effective on oral malodor control than dentifrice without triclosan and sodium bicarbonate.
키워드
sodium bicarbonate; triclosan; oral malodor; dentifrice
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